NAME:

Monica Culea

PRESENT POSITION:

Professor Dr. Babes-Bolyai UniversityBiomedical Physics Dept.,

400084 Cluj-Napoca, Romania

Tel: 0040-264-405300 fax :0040-264-591906

E-mail: culea_monica@yahoo.com; mculea@phys.ubbcluj.ro;

BIOGRAPHICAL:

Date of birth: July 8, 1951 Citizenship: Romania Home Address: Str. Mehedinti 80, ap.13 3400 Cluj-Napoca, România Tel: 0040264-575883;

LANGUAGES:

English, French

EDUCATION:

1970-1975: University Cluj-Napoca Faculty of Physics Degree - Master of Science

1990-1993: Program: Analytical Applications of Mass Spectrometry Degree - Doctor of Philosophy Area of Study - Isotopic dilution quantitative MS

PROFETIONAL AND TEACHING EXPERIECE:

1975 - 1978: Mechanical Plant, Cluj-Napoca, productive experience

1979-1997: Institute of Isotopic and Molecular Technology, Cluj-Napoca Area: Isotopic mass spectrometry, structural analysis of organic compounds using high resolution MS, metastable analysis, quantitative determination by isotopic dilution MS and GC/MS, method validation for trace analysis

2/92 - 12/92: Welcome research fellow Training at Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas, USA Program:"Applications of stable isoptope tracer in human nutrition research”

9/1994 –2002: Associate Professor Department of Atomic Physics

4/1997 –2002: SC NATEXs.r.l. Area: Food, beverage, analysis of natural extracts by GC and GC/MS.

10/2002 Lecturer Biomedical Physics Department“Babes-Bolyai” University Cluj-Napoca

10/2005 Assoc. Professor

10/2008 Professor.

TEACHING EXPERIENCE:

1990 to present: Supervisor of graduate student research and PhD adviser

1993-1994: General Physics. 1993-present: Experimental methods in atomic and molecular physics, Ambient protection, Ecology, pollutants, biomedical applications.

2002 to present Biophysics, Dosimetry and Radioprotection,

RESEARCH ACTIVITIES:

- Structural studies by GC/MS and metastable measurements

- Quantitative analysis of amino acids using ID-GC/MS for biochemical applications

-Quantitative analysis of fatty acids by GC and GC/MS

-transmembranar transport study, malabsorption and biochemical applications.

-Pharmacokinetic studies of anaestesics (procaine), theophylline and caffeine in plasma and saliva.

- UL 13C -cholesterol synthesis for metabolic study.

- Quantitative determination of VOCs, BTEX, nicotine and organophosphoric pesticides in air, water and soil.

- Natural extracts characteriation. Food and beverage analysis. Active principle extraction and characterization in herbs and red wines.

- Trihalomethanes (THMs) determination in drinking water by headspace-GC-MS; interlaboratory studies to compare headspace-GC-MS, LC-GC-MS, headspace-GC-ECD, purge&trap-GC-MS; laboratory kinetic studies;

- Metabolic diseases diagnosis by using biomarkers (amino acid fingerprint for PKU, MSUD, caffeine for cirrhosis, breath markers)

- Biotechnological applications: free amino acids and fatty acids characterization during fermentation steps of salami, yogurt, cheese Keywords: GC/MS, SIM-GC-MS, isotopic dilution, quantitative analysis, method validation, amino acids, fatty acids, transmembranar transport, pharmacokinetic studies, drugs, diagnosis, VOCs, BTEX, THMs, environmental tobacco smoke, pesticides, pollutants, headspace, aroma, herbs.

MEMBERSHIPS’:

Romanian Society of Physics

European Society of Physics

Romanian Society of Biophysics

Romanian Society of Analitical Chemistry

Romanian Society of Mass spectrometry

International Society of Built Environment, (Comity member)

HONORS:

1992 Diploma of International Agency of Atomic Energy

1986 Diploma of FEBS advanced courses “Biomembranes and diseases”

1997 Diploma of FiaTest “Quality Systems”

1999-2000,

2010 Who’s Who in the World